Koen Paemeleire obtained his Medical Degree in 1995 at the Ghent University in Belgium. He earned a PhD in Medical Sciences based on calcium signalling research with Professor Luc Leybaert at the Department of Physiology and Pathophysiology in Ghent and as a Fulbright Scholar with Professor Michael J. Sanderson at the Department of Physiology of the UMASS Medical Center, MA, USA.
He completed a five-year residency training programme in Neurology chaired by Professor Jacques De Reuck in Ghent. He trained in headache medicine with Professor Peter J. Goadsby at the National Hospital for Neurology and Neurosurgery, Queen Square, London, UK. He works as a consultant neurologist at the Department of Neurology, Ghent University Hospital, Belgium since 2004, where he runs a specialized headache clinic. He was also appointed part-time Senior Lecturer in Neurophysiology at the Department of Basic and Applied Medical Sciences, Faculty of Medicine and Health Sciences, Ghent University, Belgium.
His research focuses on the management of headache (including digital health applications most recently), neuromodulation techniques and migraine neurobiology. He is Associate Editor of the Journal of Headache and Pain. He is involved in multiple clinical trials testing CGRP pathway antibodies in the prevention of migraine and cluster headache.